Very common (10% or more): Nausea/vomiting (up to 11%)Ĭommon (1% to 10%): Abdominal pain/cramps, diarrhea Very rare (less than 0.01%): Chorea exacerbatedįrequency not reported: Loss of consciousness, epilepsy, Sydenham's chorea, transient ischemic attack, ischemic stroke, hemorrhagic stroke, stroke, cerebral hemorrhage, cerebral thrombosis LocalĬommon (1% to 10%): Application site disorder (transdermal system) Gastrointestinal Very common (10% or more): Headache (up to 33%) Postmarketing reports: Thrombosis Nervous system Rare (less than 0.1%): Venous thromboembolism, arterial thromboembolismįrequency not reported: Deep vein thrombosis, hypertension, myocardial infarction, varicose veins exacerbated, thrombophlebitis, cerebral vascular disease, mitral valve prolapse Uncommon (0.1% to 1%): Blood pressure increased Postmarketing reports: Menstrual flow reduced, withdrawal bleeding missed, post pill amenorrhea Cardiovascular Rare (less than 0.1%): Breast discharge, vaginal discharge, amenorrheaįrequency not reported: Uterine myoma, temporary infertility, cervical erosion changed, cervical secretion changed, diminution in lactation Uncommon (0.1% to 1%): Breast enlargement, breast hypertrophy, menstrual flow changed Very common (10% or more): Irregular/heavy uterine bleeding (up to 17%), menorrhagia (up to 11.6%), breast pain (up to 11.2%), dysmenorrhea (up to 11%), breakthrough bleeding/spottingĬommon (1% to 10%): Breast tenderness/discomfort, vaginitis, candidiasis, breast enlargement, breast secretion, breast tension, intermenstrual bleeding/metrorrhagia The most frequently reported side effects were headache, heavy/irregular vaginal bleeding, nausea/vomiting, acne, dysmenorrhea, weight increased, mood changed, anxiety/panic attack, breast pain, and migraines. patchy brown or dark brown discoloration of the skinĪpplies to ethinyl estradiol / levonorgestrel: oral tablet, oral tablet chewable, transdermal film.loss in sexual ability, desire, drive, or performance.decreased interest in sexual intercourse.Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.Ĭheck with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Incidence not known These side effects may go away during treatment as your body adjusts to the medicine. Some side effects of ethinyl estradiol/levonorgestrel may occur that usually do not need medical attention. twitching, uncontrolled movements of the tongue, lips, face, arms, or legs.thick, white curd-like vaginal discharge without odor or with mild odor.tenderness, pain, swelling, warmth, skin discoloration, and prominent superficial veins over the affected area.swelling, pain, or tenderness in the upper abdominal area.pain or discomfort in the arms, jaw, back or neck.light vaginal bleeding between regular menstrual periods.itching of the vagina or outside the genitals.inability to move the arms, legs, or facial muscles.dull ache or feeling of pressure or heaviness in the legs.difficult, burning, or painful urination.decrease in urine output or decrease in urine-concentrating ability.changes in skin color, pain, tenderness, or swelling of the foot or leg.breast tenderness, enlargement, discharge.Absent, missed, or irregular menstrual periods.Although not all of these side effects may occur, if they do occur they may need medical attention.Ĭheck with your doctor immediately if any of the following side effects occur while taking ethinyl estradiol/ levonorgestrel: Incidence not known Serious side effects of LarissiaĪlong with its needed effects, ethinyl estradiol/levonorgestrel may cause some unwanted effects. Women who use oral contraceptives should be strongly advised not to smoke. This risk increases with age, particularly in women older than 35 years, and with the number of cigarettes smoked. Cigarette smoking increases the risk of serious cardiovascular events from combination oral contraceptives (COC) use.
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